Scientist I, Bioinformatics

Company: Ultragenyx Pharmaceutical
Location: Novato
Posted on: February 22, 2021

Job Description:

Ultragenyx is a commercial-stage biopharmaceutical company committed to developing novel therapies for the treatment of rare and ultra-rare genetic diseases. The company has rapidly built a diverse portfolio of small molecule, monoclonal antibody, mRNA and gene therapy candidates with the potential to address debilitating genetic diseases for which the unmet medical need is high, the biology for treatment is clear, and for which there are typically no approved therapies treating the underlying disease.-- Developing new treatments for rare genetic diseases is challenging work. It takes courage, talent, and dedication to look past the easy answers and uncover new solutions that can make a meaningful impact. At Ultragenyx we push each other to perform at our very best, because we never lose sight of our mission - to make a difference in our patients' lives. Come join our team during this exciting time of growth and opportunities! During the COVID-19 Outbreak we are committed to our hiring process. The health and safety of our employees and prospective employees take priority which means at this time our process will include WebEx video discussions, interviews & onboarding. Position Summary ultrafocused - Work together to fearlessly uncover new possibilities We are seeking a Bioinformatics Scientist to fill an exciting role in our exceptional, highly collaborative Research group. The ideal candidate should have solid training in bioinformatics or related disciplines and is delivery oriented with a focus on real world impact. The candidate should also be a quick learner, extremely flexible and able to adapt to needs and new scientific advancements. This person will collaborate across all facets of our pipeline and be key in providing support to our preclinical programs.-- Responsibilities including, but not limited to:

• Provide bioinformatics support to the Ultragenyx Research group to advance our preclinical programs.
• Independently carry out bioinformatics analyses and deliver results to project teams.
• Contribute to patient identification in the field of rare genetic diseases through aiding diagnostic sequencing programs, genotype/phenotype data capture and data analysis.--
• Support the development and maintenance of a database to store genotype/phenotype information and analyze genotype-phenotype associations.
• Interpret variants through use of genomic databases and bioinformatics tools.--
• Interact with Translational Sciences, Molecular Diagnostics, Medical Affairs, Commercial, Patient Diagnosis and Ultragenyx Gene Therapy Teams and provide support to ensure best use of all relevant data impacting project decisions. Requirements:
  • PhD with 2+ years related experience OR MS with 6+ years related experience or BA/BS with 8+ years related experience. Degree in a scientific discipline or equivalent in Bioinformatics required.--
  • Expert knowledge of scientific principles and concepts.
  • Demonstrated problem-solving and data analysis skills based on body of work and record of accomplishments.
  • Depth in familiarity of public databases such as ClinVar, GEO, GTEx, GenBank and gnomAD.
  • Understanding of Sanger and NGS sequencing technologies.--
  • Familiarity with analysis of RNA-Seq, WGS and Exome sequencing data.--
  • Experience and fluency with standard software tools for high-throughput sequencing data processing.
  • Solid understanding of statistical genetics and ability to perform analysis in R, Matlab or equivalent software.--
  • Ability to independently design and perform diverse bioinformatics tasks.--
  • Programming and scripting abilities in languages, such as R, Perl, Python.
  • Familiar with Linux/Unix systems.
  • Team player with excellent communication and presentation skills and ability to thrive in a dynamic environment.-- #LI-CV1 Ultragenyx Pharmaceutical is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status. Reasonable accommodation will be provided for qualified individuals with disabilities and for qualified disabled veterans in job application procedures, as required by applicable law. If you have any difficulty using our online application system and need an accommodation due to a disability, you may contact--Talent Acquisition--by calling:--(415) 483-8800--or by--emailing--us at--talentacquisition@ultragenyx.com . For electronic email and mail inquiries, please include a description of your requested accommodation, your name and contact information. Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to:--talentacquisition@ultragenyx.com .

Keywords: Ultragenyx Pharmaceutical, Novato , Scientist I, Bioinformatics, Other , Novato, California