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Senior Research Associate 1

Company: BioMarin Pharmaceutical Inc.
Location: Novato
Posted on: May 12, 2022

Job Description:

BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind. BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients' lives.

SUMMARY:The Analytical Sciences department at BioMarin Pharmaceutical Inc. is seeking an experienced molecular and cell biologist at Senior Research Associate 1 level for research and development activities. This individual will be working on assay development for recombinant adeno-associated virus (rAAV)-based vectors. RESPONSIBILITIES:

  • Cell culture (maintenance, expansion, transduction).
  • Characterization and evaluation of performance of rAAV in cell-based assay.
  • Design, plan, and perform experiments, diligently document the results. Prioritize tasks, manage time effectively.
  • Being self-motivated and proactive.
  • Critical thinking; troubleshooting and problem solving.
  • Teamwork; present results in team meetings; conduct internal and external collaborations.
  • Flexibility in a fast-paced changing environment; be willing to accept responsibilities outside of the initial job description.EDUCATIONA degree in molecular biology, cell biology, virology or any related field, meeting the minimum requirements is Bachelor's degree with 6 years of experience, or Master's degree with 4 years of relevant experience in academia or in the biotechnological industry. EXPERIENCERequired:
    • Hands-on expertise in mammalian cell culture and molecular biology methods.
    • Analytical tools: cell-based potency assays, ddPCR, ELISA, WES/JESS, electrophoresis.
    • Prior experience with AAV characterization or analysis is required.
    • Ability to take ownership of the projects and independently lead development efforts for cell-based assays.
    • Critical thinking, excellent data analysis and interpretation skills.
    • Good verbal and written communication skills. Proficiency in Microsoft Word, Excel, and PowerPoint. Presentation of results in written and oral formats.
    • Strong ability to work in a team.Desired:
      • Assay development and qualification experience is a plus.
      • Experience with baculovirus and/or other viral vectors.
      • Flow cytometry, data analysis.

Keywords: BioMarin Pharmaceutical Inc., Novato , Senior Research Associate 1, Other , Novato, California

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