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Research Associate II, Protein Formulation Development

Company: BioMarin Pharmaceutical Inc.
Location: Novato
Posted on: January 27, 2023

Job Description:

Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard - so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients' lives. SummaryThe selected candidate will work in the Chemical, Drug Product, and Device Technologies (CPDT) team to advance therapeutic proteins, peptides, and gene therapy vectors for non-clinical, clinical and commercial applications. The candidate will work in a team responsible for parenteral dosage formulation development, product characterization, stability determination and supporting manufacturing processes for drug products. The selected candidate should thrive in a lab-based environment, possess strong analytical skills, be a self-starter, and willing to work collaboratively in a dynamic team environment. ResponsibilitiesThe candidate must exercise technical competence in the design and execution of various preformulation and formulation development experiments and projects. He or she writes protocols, executes experiments, provides quantitative analysis of data and interpretation of results, and contributes to technical reports. At times, he or she may evaluate complex methods, technologies, or laboratory equipment. The primary focus is laboratory experimental work as follows:

  • Assist in the development of formulations to support pre-clinical and clinical studies
  • Write experimental protocols and technical reports summarizing development work
  • Demonstrate technical expertise and have experience in a range of basic analytical methods
  • Employ various analytical instruments to conduct physicochemical and biophysical characterization of lead molecules
  • Provide concise and quantitative analysis of data and interpretation of experimental results
  • Possess excellent problem-solving skills and effective time management to deliver reliable results in a timely manner
  • Evaluate and establish new techniques, methods, and procedures based on evolving project demands
  • Maintain thorough and timely documentation of experiments
  • Deliver effective oral presentations to departmental and cross functional groups
  • Foster teamwork by working collaboratively within CFDD group and external collaborators Required skills
    • Strong analytical skills and instrument troubleshooting skills
    • Must be able to employ various analytical methods (HPLC, calorimetry, spectrophotometry, light scattering, Freeze Drying Microscopy, etc.) to screen and characterize drug products
    • Attention to detail and effective organizational skills
    • Able to use computers effectively for data analysis and presentation
    • Excellent communication skills, strong ability to present results in both oral and written formats
    • Be a team player Education/Experience
      • Bachelors degree in Chemistry, Pharmaceutical Chemistry, Chemical Engineering, Biochemistry, or related field plus at least 4 years experience in biotech or pharmaceutical development industry.
      • Masters degree in Chemistry, Pharmaceutical Chemistry, Chemical Engineering, Biochemistry, or related field plus at least 2 years experience.PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Keywords: BioMarin Pharmaceutical Inc., Novato , Research Associate II, Protein Formulation Development, Other , Novato, California

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